
Medicine Central expert articles
Expert Articles
Evidence-led articles for UK primary care from Medicine Central contributors, bringing practical clinical perspective and research insight together.
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Clinical expert insight for UK primary care
These articles bring named contributors' perspectives to clinical evidence, professional learning and the day-to-day questions faced in UK primary care. Browse the newest articles below, or explore our clinical evidence library and free CPD webinars for related learning.
Expert articles
All published contributor articles, newest first.


Clinical trials in general practice: answering the safety question
Dr Fatima Tahir explains the safeguards that underpin clinical trials in general practice, from ethical review and informed consent to Good Clinical Practice and ongoing safety monitoring.

LatAm-FINGERS: Can lifestyle intervention help prevent dementia?

The Change We Forgot to Finish Talking About
This is a chance for women to get their mojo back.

How to Get Started in Research as a Primary Care Professional in the UK

Semaglutide for secondary cardiovascular prevention: An update that may have gone unnoticed – what NICE TA1152 means for primary care
NICE TA1152 establishes semaglutide 2.4 mg as a secondary cardiovascular-prevention treatment for adults with established cardiovascular disease and a BMI of at least 27 kg/m². Niraj Lakhani considers what this means for primary care.

FIVE questions to ask before you switch to ambient AI

Chronic Kidney Disease in Primary Care: Small Changes That Make a Big Difference
CKD is common, but progression is not inevitable.

Primary Care Research: From an Optional Extra to an Essential Part of Modern General Practice
Almost 90% of NHS patient contacts happen in primary care, yet most research still happens somewhere else. Dr Fatima Tahir on why that gap matters, and what practices stand to gain from closing it.

Triglyceride-associated cardiovascular risk: Leaving risk on the table
Despite excellent LDL-cholesterol management, 1 in 3 patients with established ASCVD will experience a recurrent event within three years. Elevated triglycerides represent a major — yet frequently overlooked — driver of residual cardiovascular risk. Moudy Khodadi, Advanced Pharmacist Lipid Clinic, explains the mechanism, the evidence, and what actually works.

One patient, three pains: a palliative care case study in opioid titration
This week, our expert insights will guide you through a case study from Jan Brassington’s webinar, ‘Managing Pain in Palliative Care.’ You can now watch it as an on-demand video on our CPD Webinars page!

Appraising the Longevity Supplement Stack with the Latest Evidence
Patients are arriving in clinic with curated supplement stacks, convinced that longevity science has delivered a shortcut to a longer, healthier life. The evidence tells a more sobering story.

From PCOS to PMOS: A Practical Update for GPs
PCOS has been officially renamed Polyendocrine Metabolic Ovarian Syndrome (PMOS) following international consensus in 2026. This expert update covers the new diagnostic criteria, holistic management approach, and what this means for primary care.

GLP-1 Prescribing Is Now a Minefield. Here's a Practical Route Through It
Three NICE pathways for the same class of drug, each with its own eligibility criteria, funding route, and stopping rule. Kashif Shakoor maps a practical route through the complexity.

Making sense of abnormal liver blood tests: a MASLD heuristic for primary care
Around one in five adults have abnormal liver blood results. However, in the BALLETS primary care group, only 2.5% had a specific liver disease.

Lipoprotein(a): The Overlooked Cardiovascular Risk Marker You Should Know About

Small Drop, Big Impact: Why Getting Blood Pressure to 120/80 Matters
Blood pressure management sits at the heart of cardiovascular prevention, yet many patients remain under-treated against optimal targets.

Sleep as a Vital Sign? Why Primary Care May Need to Rethink Its Approach
Primary care routinely measures blood pressure, BMI and smoking status; however, one of the strongest predictors of long-term health outcomes is often left unassessed - sleep.

The Peptide Pandemic
What UK primary care needs to understand about the grey market peptide trade
ADHD prescribing in primary care: what GPs need to know
Rising ADHD referrals means more GPs managing shared-care stimulant prescribing. This week's article is a GP guide to shared-care monitoring, red flags and drug interactions, with a free downloadable cheat sheet.
AI scribes and the changing shape of clinical documentation
Dr Frederick Reynolds, a GP using ambient scribes day-to-day, has written the kind of thoughtful, first-hand review these tools deserve.
LDL Elevation in Menopause - Interpreting Lipids in Primary Care
From raised LDL to a new non-hormonal drug class and the largest HRT safety study to date, this week is all menopause in primary care.
